Paricalcitol may improve oxidative DNA damage on experimental amikacin-induced nephrotoxicity model
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چکیده
منابع مشابه
Evaluating the effects of galbanic acid on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes
Objective: Ferula szowitsiana has been widely used for medicinal purposes around the world. The anti-oxidant effect of F.szowitsiana had been proved. The current study aims to determine the protective effects of galbanic acid, a sesquiterpene coumarin from F. szowitsiana, against hydrogen peroxide (H2O2) - induced oxidative DNA damage in human lymphocytes. Materials and Methods: Human lymphocyt...
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From the Department of Pharmacology, Lady Hardinge Medical College & Associated Smt. Sucheta Kriplani.Hospital, New Delhi-110 001 Correspondence to : Dr Harmeet Singh Rehan, Professor and Head, Department of Pharmacology, Lady Hardinge Medical College & Associated Smt. Sucheta Kriplani.Hospital, New Delhi-110 001. E-mail: [email protected] Amikacin and Diclofenac Induced Nephrotoxicity: ...
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Occupational noise enhances the risk of several cardiovascular and non-cardiovascular diseases. The reason behind the drastic effects of noise exposure is the excessive generation of reactive oxygen species molecules. The present study investigates oxidative stress due to occupational noise exposure in 192 male smoking workers exposed to normal noise (sound level ≤80 dBA), low noise (sound leve...
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Nephrotoxicity is a major complication and a dose limiting factor for cisplatin therapy. Recent evidence suggests that inflammation and oxidative stress may contribute to the pathogenesis of cisplatin-induced acute renal failure. Curcumin is claimed to be a potent anti-inflammatory and antioxidant agent. The present study was performed to explore the effect of curcumin against cisplatin-induced...
متن کاملMitochondrial oxidative DNA damage in experimental autoimmune uveitis.
PURPOSE In experimental autoimmune uveitis (EAU), recent work has demonstrated that retinal damage involves oxidative stress early in uveitis, before macrophage cellular infiltration. The purpose of this study was to determine whether oxidative mitochondrial DNA damage occurs early in EAU, before leukocyte infiltration. METHODS Lewis rats were immunized with S-antigen mixed with complete Freu...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2016
ISSN: 0886-022X,1525-6049
DOI: 10.3109/0886022x.2016.1158071